In vitro Digestion
digestion models aim at reproducing the digestive processes
occurring at various stages of the gastrointestinal tract (mouth,
stomach, small intestine and colon/microbiota). They can be static with
fixed parameters (pH, enzyme concentration) or dynamic with parameter
variations based on in vivo data. They can mimic a single step, for
instance intestinal digestion, or combine several steps to better
reflect the overall digestion.
in vitro models are based on the availability of in vivo data,
including pH variations and enzymes concentrations, as well as on the
availability of the main digestive enzymes produced in the stomach and
by the pancreas.